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Penehyclidine hydrochloride

CAS No. 151937-76-7

Penehyclidine hydrochloride( —— )

Catalog No. M35531 CAS No. 151937-76-7

Penehyclidine hydrochloride (Penequinine hydrochloride) is an?M1?and?M3?antagonist and activates?NF-κB?in lung tissue.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Penehyclidine hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Penehyclidine hydrochloride (Penequinine hydrochloride) is an?M1?and?M3?antagonist and activates?NF-κB?in lung tissue.
  • Description
    Penehyclidine (Penequinine) hydrochloride, a anticholinergic agent, is a selective antagonist of M1 and M3 receptors. Penehyclidine hydrochloride activates NF-kβ in lung tissue and inhibits the release of inflammatory factors. Penehyclidine hydrochloride can alleviate the pulmonary inflammatory response in rats with chronic obstructive pulmonary disease (COPD) undergoing mechanical ventilation.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    NF-κB
  • Recptor
    NF-κB | AChR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    151937-76-7
  • Formula Weight
    351.91
  • Molecular Formula
    C20H30ClNO2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Cl.OC(COC1CN2CCC1CC2)(C1CCCC1)c1ccccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Zhi-Yuan Chen, et al. The Mechanism of Penehyclidine Hydrochloride and Its Effect on the Inflammatory Response of Lung Tissue in Rats with Chronic Obstructive Pulmonary Disease During Mechanical Ventilation. Int J Chron Obstruct Pulmon Dis. 2021 Mar 31;16:877-885.?
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