Home - Products - Apoptosis - NF-κB - Penehyclidine hydrochloride

Penehyclidine hydrochloride

CAS No. 151937-76-7

Penehyclidine hydrochloride( —— )

Catalog No. M35531 CAS No. 151937-76-7

Penehyclidine hydrochloride (Penequinine hydrochloride) is an?M1?and?M3?antagonist and activates?NF-κB?in lung tissue.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 214 Get Quote
5MG 337 Get Quote
10MG 501 Get Quote
25MG 775 Get Quote
50MG 1040 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Penehyclidine hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Penehyclidine hydrochloride (Penequinine hydrochloride) is an?M1?and?M3?antagonist and activates?NF-κB?in lung tissue.
  • Description
    Penehyclidine (Penequinine) hydrochloride, a anticholinergic agent, is a selective antagonist of M1 and M3 receptors. Penehyclidine hydrochloride activates NF-kβ in lung tissue and inhibits the release of inflammatory factors. Penehyclidine hydrochloride can alleviate the pulmonary inflammatory response in rats with chronic obstructive pulmonary disease (COPD) undergoing mechanical ventilation.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    NF-κB
  • Recptor
    NF-κB | AChR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    151937-76-7
  • Formula Weight
    351.91
  • Molecular Formula
    C20H30ClNO2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Cl.OC(COC1CN2CCC1CC2)(C1CCCC1)c1ccccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Zhi-Yuan Chen, et al. The Mechanism of Penehyclidine Hydrochloride and Its Effect on the Inflammatory Response of Lung Tissue in Rats with Chronic Obstructive Pulmonary Disease During Mechanical Ventilation. Int J Chron Obstruct Pulmon Dis. 2021 Mar 31;16:877-885.?
molnova catalog
related products
  • Cynaropicrin

    Cynaropicrin, a sesquiterpene lactone found in artichoke (Cynara scolymus), has anti-hepatitis C and trypanosome activity and inhibits NF-κB activation.

  • Penehyclidine hydroc...

    Penehyclidine hydrochloride (Penequinine hydrochloride) is an?M1?and?M3?antagonist and activates?NF-κB?in lung tissue.

  • Chrysotoxine

    Chrysotoxine inhibits 6-hydroxydopamine induced apoptosis in SH-SY5Y cells via NF-κB modulation and mitochondria protection.